As we are developing an increased understanding of the physiological function of cannabinoids it is becoming evident that they are involved in the pathology of some diseases, particularly neurological disorders.
Cannabinoids may induce both growth and death in a number of cells, including neurons - in the central nervous system (CNS). Experimental evidence indicates that cannabinoids protect neurons from damage induced by toxic and traumatic insults. This “neuroprotective” effect of cannabinoids has proven to be effective in the treatment of neurodegenerative disorders, including Charcot-Marie-Tooth (CMT) disease as well as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Parkinson’s disease, and injuries incurred when the brain is deprived of oxygen such as in a stroke.
THC and / or CBD is helpful for aspects of PD such as tremor, stiffness, insomnia, dystonia, pain, dyskinesias and weight loss.
Because the history and politics of marijuana trigger such strong emotions, it is understandable that the public has begun to think of THC and CBD as unique substances with their own rules. But they should not be viewed this way. They are chemicals found in plants that have effects on the human brain and body and are proven to help humans cope with some difficult medical symptoms. And if they are used by humans to cope with a medical symptom, then they are medications.
To that end, we need to treat THC and CBD as the medications that they are and subject them to the same standards that we do any medication. Hence, the clinical trials described below:
Clinical Trials in Parkinson’s disease with CBD and THC
were conducted on six patients with psychosis. Psychotic symptoms decreased. In a second trial, an open label study of CBD was conducted on four patients with REM behavior sleep disorder. Symptoms decreased. In a third, a double blinded trial of 21 patients were treated with CBD. Their quality of life scores improved. In another, patients at a movement disorders center were asked to fill out an anonymous questionnaire about their experience with cannabis. Of the 84 patients who admitted to using cannabis, 39 described substantial improvement of PD symptoms including a reduction of tremors and dyskinesias.
Supportive evidence is also readily available regarding the benefits of medical marijuana to people suffering from Multiple Sclerosis.
For further information - Whatsapp or call Azelda.
Back To Top